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Naps
Optimize Your Medications with PGx Testing
Understand how your unique DNA impacts your response to medications, so you can skip the trial-and-error approach and improve medication effectiveness with treatments that actually work for you.
We will never share your data
We follow HIPAA and GDPR policies
We have World-Class Encryption & Security
Rated 4.7/5 from 750+ reviews
200,000+ users, 2,000+ doctors & 80+ businesses
Personalized Medication Guidance Based on Your DNA
Our Pharmacogenomics (PGx) Test provides personalized insights to help you and your doctor choose the most effective medications. This simple at-home test offers a detailed report with recommendations based on your genetic profile.
- Get personalized medication advice based on your unique DNA
- Convenient at-home testing
- Clear, actionable report with insights on 50+ medications
People love us
Why Get a PGx Test
Pharmacogenomics testing shows how your genes impact the way your body processes medications. This means you can avoid the trial-and-error approach to treatment and find the medications that work best for you.
Understand how your genetic makeup affects your response to different medications for more personalized treatment.
Reduce side effects and improve effectiveness by working with your doctor in choosing the right medication for your DNA.
Get trusted recommendations for over 50 medications, supported by guidelines from specialized organizations.
See How Your Genes Affect Medication Effectiveness
Our PGx test dives deep into key genes that influence how your body processes medications. With insights on over 50 medications across categories like cardiovascular and psychotropic drugs, you and your doctor will have the info you need to make smarter choices about your treatment.
People love us
Unlock Your PGx Report Today
Uncover how your genes affect your response to over 50 medications and use personalized insights to choose the most effective treatments for your unique genetic profile.
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DNA DAY 45% OFF SALE
Ultimate Bundle
- Includes PGx Report & Full Health Analysis!
- SelfDecode DNA Kit
- 1250+ DNA Health Reports with Personalized Recommendations
- Lifestyle & Longevity Risk Assessments
- 24/7 AI Health Coach & Unlimited Labs Analyzer Access
- +130 Medical Reports & Methylation Pathway
- Family Planning (Carrier Status) & Ancestry Reports
We will never share your data
We follow HIPAA and GDPR policies
We have World-Class Encryption & Security
Rated 4.7/5 from 750+ reviews
200,000+ users, 2,000+ doctors & 80+ businesses
More Than Pharmacogenomics Testing
SelfDecode is a complete health optimization platform, giving you all the tools to take charge of your well-being:
Personalized Recommendations
Get tailored diet, supplement, and lifestyle suggestions based on your health risks and goals.
1250+ DNA Health Reports
Explore personalized insights into 1250+ health topics using advanced polygenic risk scores.
Lab Tracking
Optimize 4,000+ lab markers with personalized guidance.
Nutrition Planner
Receive custom meal plans, recipes, and shopping lists tailored to your body.
Suggested Labs
Get a personalized list of suggested lab tests based on your DNA & health goals.
SNP & Gene Search Tool
Discover your genotype for any SNP in our database of 200M+ genetic variants.
FAQs
What exactly is Pharmacogenomics (PGx) ?
Pharmacogenomics (PGx) is the study of how your unique genetic makeup influences your body's response to medications. Specific genes control how your body metabolizes (breaks down), transports, and interacts with drugs. Variations (called genetic variants or polymorphisms) in these genes can make a drug more effective, less effective, or increase your risk of side effects at standard doses. Think of it as personalized medicine based on your DNA.
How does the PGx test help determine my medication response?
Depending on your unique genetic makeup, you may process a medication:
Faster than normal, which may cause the medication to not provide the desired effect
Slower than normal, which may increase the risk of side-effects
In an unusual way, which may affect safety or effectiveness
This is because we all process medications differently.
If we are all given the same medication at the same dose, we react in four different ways:
They drug will work but will cause side effects
The drug won’t work and will also cause side effects
The drug won’t work but there will be no side effects
The drug will work and there will be no side effects
By testing our DNA, we can work out how we may react to each medication.
Thus testing can help your doctor determine the right medication at the right dose for you.
What are the benefits of PGx testing?
Improve treatment outcomes: Experience better health results with medications that work for you.
Minimize the risk of side effects: Reduce the chances of experiencing adverse reactions.
Optimized drug selection and dosing: Receive the most appropriate medications at the correct dose from the start.
Reduce long-term health impacts: Protect your health by avoiding medications that don’t work or cause harm.
Save time and money: Skip the trial-and-error process of finding the right medication.
Fast-track your treatment: Get on the path to the right medication, at the right dose, the first time.
Pharmacogenomic testing is a powerful tool that empowers both you and your doctor to make informed, personalized decisions about your medication, helping you achieve better health outcomes quickly and safely.
How is your PGx testing different?
Our PGx test analyzes your DNA to identify genetic variants influencing how your body processes over 50 different medications. Using guidelines from trusted sources such as the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the FDA, our detailed report provides personalized prescribing guidance. [View sample report here].
What are the limitations of PGx testing?
Efficacy and safety of medications is not solely dependent on your DNA. Other factors will impact whether a medication is safe and effective or not and at what dose, including general health, environmental factors, or other medications.
What medication checks are covered in this report?
Our PGx report covers a wide range of medications across various categories, including cardiovascular drugs, antidepressants, proton pump inhibitors, and pain relievers. [See full drug list in the sample report, pages 5-6]
What do terms like "Metabolizer Type" (e.g., Poor, Intermediate, Normal, Ultrarapid) mean in the report?
Your "metabolizer type" describes how quickly your body is predicted to process certain drugs based on your genetics for specific enzyme-coding genes (like CYP2C19, CYP2C9, CYP2D6 etc.).
Normal Metabolizer (NM): Processes the drug as expected at standard doses
Intermediate Metabolizer (IM): Processes the drug slower than normal. Standard doses might lead to higher drug levels and potential side effects
Poor Metabolizer (PM): Processes the drug much slower than normal. Standard doses could lead to significantly higher drug levels and increased risk of toxicity.
Rapid/Ultrarapid Metabolizer (RM/UM): Processes the drug faster/much faster than normal. Standard doses might be cleared too quickly, potentially reducing the drug's effectiveness.
The report explains your specific metabolizer type for relevant drug-gene interactions.
What kind of information will the PGx report provide?
Our report includes:
Personalized prescribing guidance categorized into 'Standard Precautions' and 'Use With Caution'.
Specific genetic variants you possess and their impact on drug metabolism.
Clear recommendations for medication dosages, potential risks, and alternative treatments where applicable. [Explore a detailed prescribing guidance example on pages 7-9 of our sample report]
How accurate is the SelfDecode PGx test?
Our testing is performed in a CLIA-certified laboratory, ensuring high standards of accuracy and reliability for the specific genetic variants we analyze. The interpretation of how these variants affect drug response is based on established scientific evidence and guidelines from leading pharmacogenomic organizations like CPIC, FDA, PharmGKB, and DPWG (as mentioned on page 3 of our sample report).
All recommendations have evidence-based ratings:
⭐⭐⭐ High-level evidence from clinical guidelines or FDA labels.
⭐⭐ Moderate-level evidence from multiple studies.
⭐ Preliminary or limited evidence
We base our guidance on recognized standards from organizations like CPIC and FDA.
Does a PGx test tell me about the chance of side effects or adverse reactions?
Yes, PGx testing can indicate your risk of certain side effects or adverse reactions to medications, allowing your doctor to adjust dosages or choose alternative therapies proactively. For example, it can highlight increased muscle pain (myopathy) risks from specific statins.
Can this PGx test affect my current prescriptions?
This test provides crucial insights for your healthcare provider but should not prompt you to alter any medication independently. Always consult your doctor to interpret your results before changing treatments.
Can PGx testing replace consultations with my healthcare provider?
No. PGx test complements your healthcare provider's clinical judgment by offering valuable genetic insights into your medication response. Always discuss results and medication adjustments with your healthcare provider.
What if my doctor isn't familiar with PGx testing?
Pharmacogenomics is a growing field, and while many providers are knowledgeable, some may be less familiar. Your report includes references to established guidelines (CPIC, FDA) that your doctor can consult. You can also point them to resources on the CPIC website (cpicpgx.org) or PharmGKB (pharmgkb.org). The report itself explains the core concepts clearly.
Who can benefit most from PGx testing?
Everyone can benefit, especially those who:
Are on multiple medications.
Experience adverse reactions or poor effectiveness from current medications.
Are beginning new medications with known genetic influences.
Does insurance cover this test?
Currently, most insurance plans do not cover the cost of methylation testing. But you can use your FSA/HSA card to pay for this test
How secure is my genetic data?
Your privacy is a top priority & that’s why we:
Will never share or sell your data. Ever
Give you free access to your raw data
Follow HIPAA and GDPR policies
Use world-class encryption methods
Anonymize genetic data within our own systems
Store genetic and account information separately
Let you download & delete your data whenever you want
Don’t allow secondary data usage
Have a team dedicated to security & privacy
How do I take the PGx test?
The test is simple and non-invasive, using a cheek swab to collect your DNA sample. You can complete the test at home and mail it back to our laboratory for processing. Results are typically available in 2-4 weeks after our lab receives the sample.
Unlock Your PGx Report Today
Uncover how your genes affect your response to over 50 medications and use personalized insights to choose the most effective treatments for your unique genetic profile.
Shipping Worldwide
HSA/FSA Eligible
DNA DAY 45% OFF SALE
Ultimate Bundle
- Includes PGx Report & Full Health Analysis!
- SelfDecode DNA Kit
- 1250+ DNA Health Reports with Personalized Recommendations
- Lifestyle & Longevity Risk Assessments
- 24/7 AI Health Coach & Unlimited Labs Analyzer Access
- +130 Medical Reports & Methylation Pathway
- Family Planning (Carrier Status) & Ancestry Reports
We will never share your data
We follow HIPAA and GDPR policies
We have World-Class Encryption & Security
Rated 4.7/5 from 750+ reviews
200,000+ users, 2,000+ doctors & 80+ businesses
SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode strongly encourages those who use our service to consult and work with an experienced healthcare provider as our services are not to replace the relationship with a licensed doctor or regular medical screenings.